Advik Singh
Have you ever felt more tired than usual, noticed a drop in your sex drive, or struggled with energy and mood? You might chalk it up to stress or aging, but what if it’s something deeper?
Let’s read about a condition that many men don’t talk about enough: hypogonadism and how it can affect something as important as fertility. If you or someone you care about is dealing with low testosterone, this guide can help clear the confusion and give you real answers.
Hypogonadism happens when the body doesn’t produce enough testosterone, a hormone that plays a big role in men’s health, including sperm production, sex drive, mood, and muscle strength.
There are two types:
Primary hypogonadism – The problem starts in the testes.
Secondary hypogonadism – The issue begins in the brain (the pituitary gland or hypothalamus), which controls hormone signals.
Testosterone plays a key role in sperm production, and having low testosterone levels in the blood doesn’t mean a man is infertile.
Here’s why:
Sperm production is driven by multiple hormones, especially FSH (follicle-stimulating hormone) and LH (luteinising hormone).
Testosterone is still important, but what truly matters is the testosterone level inside the testes, not just what's measured in the bloodstream.
In fact, the concentration of testosterone within the testes is much higher than in the blood, and that's what supports healthy sperm production.
Low testosterone does not directly cause infertility. While testosterone is necessary for sperm production, it’s not the only hormone involved.
FSH (Follicle-Stimulating Hormone)
LH (Luteinizing Hormone)
Hypogonadism typically doesn’t resolve on its own. If caused by issues in the testes (primary hypogonadism), it’s usually permanent and may require long-term treatment, such as testosterone therapy.
However, if it's due to factors like stress, being overweight, or certain medications, secondary hypogonadism, it might be temporary. Lifestyle changes, medications, or treating the underlying cause can often help restore hormone levels and manage the condition.
A few of the best treatments for hypogonadism are:
Testosterone Replacement Therapy (TRT): It is common for male hypogonadism:
Restores testosterone and relieves symptoms (fatigue, low libido, ED, depression, muscle loss).
Administered via injections, gels, patches, or implants.
Hucog HP 10000IU Injection: Which contains Chorionic Gonadotropin, may stimulate testosterone and sperm production in men.
Hormone Replacement Therapy (HRT): Female hypogonadism is treated with often combining estrogen, progesterone, and sometimes low-dose testosterone.
Underlying conditions may require:
Medications to stimulate hormone production.
Treatment of root causes (e.g., tumors).
Here are some of the signs of high testosterone:
Increased muscle mass
Reduced body fat
Oily skin or acne
Excess facial or body hair
Deeper voice
High sex drive
Mood swings or aggression
Risk-taking behavior
Trouble sleeping
Irregular or missed periods
Excess facial/body hair (hirsutism)
Acne
Deepening of the voice
Thinning scalp hair
Increased muscle tone
To confirm hypogonadism, doctors typically use a combination of blood tests and sometimes imaging tests. Here are the most common ones:
Total Testosterone Test
Free Testosterone Test
Luteinizing Hormone (LH)
MRI of the brain (pituitary gland)
Testicular ultrasound
Testosterone peaks at the age of 18 - 20 years of 20’s and then gradually decreases after the age of 30 years by about 1% per year on average.
This decline is a normal part of aging, but lifestyle, health conditions, and other factors can influence how quickly or noticeably testosterone levels drop over time.
Risks of testosterone therapy are:
Acne and oily skin
Worsening of sleep apnea
It may aggravate heart conditions.
Fluid retention
Breast enlargement (gynecomastia)
Testicular shrinkage
Lower natural testosterone production
Reduced sperm count → Possible infertility
Increased red blood cells → Risk of clots, stroke, or heart attack
May enlarge the prostate (BPH risk)
Possible (but unclear) link to prostate cancer
Few of the ways to prevent hypogonadism are:
Maintain an active lifestyle
Eat a balanced diet and keep a healthy weight.
Avoid anabolic steroids
Limit alcohol intake
Manage chronic conditions (e.g., diabetes, high blood pressure)
Get enough sleep
Reduce stress
Avoid harmful chemicals
Regular check-ups for early detection of issues
Men with low testosterone can still have kids, but it depends on the cause of the low levels. In some cases, low testosterone affects sperm production. However, treatments like hormone therapy can help restore fertility.
However, testosterone replacement therapy (TRT) can actually lower sperm production, so it’s usually avoided for men who want to have children. Fertility treatments or assisted reproductive techniques can be options for men struggling with low testosterone and fertility. With the right support, many men with low testosterone can still become fathers.