# DeSci in Future, a16z

By [phas3](https://paragraph.com/@phas3) · 2022-02-16

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In February 2022, we published a [Decentralised Science (DeSci) guide](https://future.a16z.com/what-is-decentralized-science-aka-desci/) in the online magazine, [Future](https://future.a16z.com/) by a16z.

This introductory guide covers how DeSci came to be, what its defining features are, what the major debates and open questions are within the movement, and where the greatest opportunities and challenges lie.

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*Originally published on [phas3](https://paragraph.com/@phas3/desci-in-future-a16z)*