# recent

**Published by:** [Superme002](https://paragraph.com/@superme002/)
**Published on:** 2021-10-28
**URL:** https://paragraph.com/@superme002/recent

## Content

In recent years, large-scale genome sequencing projects, including both organism-specific and environmental metagenomic projects, provided a large volume of gene and protein sequence information. However, selenoprotein genes are almost universally misannotated in these datasets because UGA has the dual function of encoding Sec and terminating translation, and only the latter function is recognized by current annotation programs. Several bioinformatics tools have been developed to address this problem and can be used to identify selenoprotein genes . These programs have successfully identified many new selenoproteins in both prokaryotic and eukaryotic genomes, as well as in the Sargasso Sea environmental samples

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