Weakest is a relative term. Humans may appear physically weak, but adversity breeds innovation. Of all the known races in this galaxy not one had developed within the medical field quite like those humans from Sol.

Why would we?

We were foolish. We never developed X-ray machines, why bother when our bones never shattered? Anesthetic, pssh, no need to bother we don’t even feel pain. Vaccine research, what would we research if we’ve never even had what humans called the common flu? The entire galaxy was so unprepared, yes, we had our warships, attached with the best warp drives and plasma turrets our species could develop. But, bio-warfare is unfathomable! No plans in place, no way to prepare for what was next.

It was the Humans that started this super plague, the species with advanced understanding of medicine! Once it spread beyond a critical point, we couldn’t even slow the spread. Of course, our response was to annihilate the humans, it would be easy with their pathetic frame. Each specie's population was beginning to die by the millions.

As the combined strength of the greatest military might's in the galaxy knocked on Human’s door step, a single human ship came out. They did not offer to surrender, did not offer an apology or did not even beg. Instead Humans sent a single message,

“To those who wish to live to see another cycle shall offer your best technology to us. In return we will save your people with this vaccine.”

The alien armada sat stunned, knowing they would have to submit to the Humans. If they gave the best technology to them even with the superior warriors, they could never get revenge. It is either to risk the entire galaxy to destroy the Humans now or forever be under their thumb.

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Edit: Thanks all for the comments, I enjoyed reading them, and this is my very first r/WritingPrompts story! I won't be continuing this story but I'll consider additional parts in future stories.