Previously, on March 23, the official website of the State Food and Drug Administration disclosed that in accordance with the special approval procedures for drugs, it conditionally approved the listing of the Class 1 innovative drug Laritevir Tablets (trade name: Le Ruiling) declared by Guangdong Zhongsheng Ruichuang Biotechnology Co., Ltd. . Laritevir tablets are oral small-molecule drugs for the treatment of novel coronavirus infection.

Up to now, a total of 6 new crown oral antiviral drugs have been approved for marketing in China, namely Pfizer Paxlovid (3CL), Simcere Pharmaceuticals (3CL), Merck & Co. (RdRp), Real Biological Azvudine (RdRp) and the latest approved Zhongsheng Pharmaceutical Le Ruiling (3CL).

The peak of the next wave of epidemics will appear locally

The new crown epidemic is basically over, how big is the demand for the 6 new crown oral drugs in China? At the meeting, academician Zhong Nanshan said that the term "basically over" is relative to the peak of the new crown infection last year. At present, everyone is predicting the next wave of peaks. Different scholars have different predictions. Some people say that around May, because of the vaccine The protection time is half a year, and some people say after September.

According to the monitoring of the epidemic situation in Singapore and the United States, Academician Zhong Nanshan believes that the peak of the new crown will appear locally in the future, but it will not be nationwide. The research and development of new drugs and vaccines will not be interrupted, so we can be prepared. In order to better cope with the possible new wave of epidemic peaks, the country is developing a new crown vaccine against new mutant strains, which is expected to be available in a few months. Another study found that people in the mixed immune state of "vaccine + breakthrough infection" will have a protection period of 6 to 8 months.

Zhong Nanshan: The requirement to wear a mask can be adjusted

Recently, many places across the country no longer require passengers to wear masks when taking the subway. Some studies also believe that the winter and spring influenza epidemic seasons are characterized by "lag" and "high-level epidemics", both of which are closely related to non-pharmaceutical interventions such as "wearing masks". As the weather gets warmer, should we still wear masks?

In this regard, academician Zhong Nanshan believes that in the past three years, wearing a mask has been a good and effective means of preventing pathogens, but at the current stage of the epidemic, wearing a mask can become a non-mandatory measure. "The crowd is exposed to pathogens such as influenza for a long time, and the nasal cavity lacks stimulation, which is not conducive to the formation of human natural immunity. After entering April, if conditions permit, it is recommended not to wear a mask."

At present, the subways of Shanghai, Guangzhou, Chengdu, Nanjing and other cities no longer make mandatory requirements for passengers to wear masks. Even if they don't wear masks, they can take the subway normally.

Previously, on March 13, the Ministry of Education, the National Health Commission, and the National Bureau of Disease Control and Prevention jointly issued the "Notice on Printing and Distributing the Technical Plan for the Prevention and Control of Novel Coronavirus Infection in Colleges and Universities, Primary and Secondary Schools, and Kindergartens (Seventh Edition)", It is clarified that colleges and universities, primary and secondary schools do not require teachers and students to wear masks; children in kindergartens do not wear masks when they are in the kindergarten, and teachers and staff are not required to wear masks when they are in the kindergarten.

But in view of the high incidence of infectious respiratory diseases in spring, such as influenza A, etc., wearing a mask is still a very effective self-protection measure. Many experts recommend that these three groups of people still wear masks: the elderly who have not been infected with the new crown, young children, and people with low immunity.