
i have no pharma background and i can't stop reading about this.
Let me be upfront about something before we go any further. I have never worked in the biotech or pharma. I have no background in biology, chemistry, or medicine beyond what a curious person picks up over a lifetime of reading. I do not hold shares in any drug company, have no consulting relationship with any research institution, and no one is paying me to have opinions about AlphaFold or clinical trial design. I am, by any reasonable definition, an outsider. What I can offer is the perspect...

i have no pharma background and i can't stop reading about this.
Let me be upfront about something before we go any further. I have never worked in the biotech or pharma. I have no background in biology, chemistry, or medicine beyond what a curious person picks up over a lifetime of reading. I do not hold shares in any drug company, have no consulting relationship with any research institution, and no one is paying me to have opinions about AlphaFold or clinical trial design. I am, by any reasonable definition, an outsider. What I can offer is the perspect...

(a rollup) on rollups
If you've been caught up in the midst of the ongoing discourse on rollups, you're not the only one. This concept has the ecosystem buzzing with conflicting definitions and a divide in the argument. And, if you're still scratching your head trying to make sense of it, let's kick things off with a metaphor to set the scene.Note that this post isn’t attempting to dive deep, be comprehensive or focus on specific projects. The goal is to walk through popular rollup designs and ...

(a rollup) on rollups
If you've been caught up in the midst of the ongoing discourse on rollups, you're not the only one. This concept has the ecosystem buzzing with conflicting definitions and a divide in the argument. And, if you're still scratching your head trying to make sense of it, let's kick things off with a metaphor to set the scene.Note that this post isn’t attempting to dive deep, be comprehensive or focus on specific projects. The goal is to walk through popular rollup designs and ...

this post is protected from “wasm will replace javascript bs”.
a version of this blog is originally published here. co-authored by: @0xDinoEggsThe Inception of WasmEvolution of web contentThe web has come a long way in history. From simple static pages to dynamic and interactive websites, there was always a need for more sophisticated content to be available and rendered on different operating systems and devices. This, of course, meant interacting with and accessing various elements within the HTML document, and hence JavaScript was introduced. Although...

this post is protected from “wasm will replace javascript bs”.
a version of this blog is originally published here. co-authored by: @0xDinoEggsThe Inception of WasmEvolution of web contentThe web has come a long way in history. From simple static pages to dynamic and interactive websites, there was always a need for more sophisticated content to be available and rendered on different operating systems and devices. This, of course, meant interacting with and accessing various elements within the HTML document, and hence JavaScript was introduced. Although...

On Scalability, Transparency and Argument of Knowledge: ZK-STARK
The Great Data HeistIt's a digital world we live in, and with every click, every search, and every purchase, we're creating a digital trail of our lives. However, the question remains, who has access to our data, and what are they doing with it? The truth is, our data is up for grabs, and it's being sold to the highest bidder. But what if there was a way to protect our data and identities, even from the organizations we have to trust?The Weak Links in the Chain of TrustWe rely ...

On Scalability, Transparency and Argument of Knowledge: ZK-STARK
The Great Data HeistIt's a digital world we live in, and with every click, every search, and every purchase, we're creating a digital trail of our lives. However, the question remains, who has access to our data, and what are they doing with it? The truth is, our data is up for grabs, and it's being sold to the highest bidder. But what if there was a way to protect our data and identities, even from the organizations we have to trust?The Weak Links in the Chain of TrustWe rely ...

A Non-Mathematical Introduction to Zero Knowledge Proof
00: Setting the SceneImagine you're playing a game of 20 Questions with a friend. Your friend has picked a secret word, and it's your job to figure it out by asking questions. But there's a twist: your friend has a rule that they can't tell you the secret word directly. They can only answer your questions with a yes or a no.— What are zero knowledge proofs?A zero-knowledge proof is a way for one person (the prover) to prove to another person (the verifier) that they know s...

A Non-Mathematical Introduction to Zero Knowledge Proof
00: Setting the SceneImagine you're playing a game of 20 Questions with a friend. Your friend has picked a secret word, and it's your job to figure it out by asking questions. But there's a twist: your friend has a rule that they can't tell you the secret word directly. They can only answer your questions with a yes or a no.— What are zero knowledge proofs?A zero-knowledge proof is a way for one person (the prover) to prove to another person (the verifier) that they know s...

DAOs within DAOs? Too Complicated!
As DAO continues to evolve, a new type of subculture will emerge: the SubDAO. These smaller, specialized DAOs have been gaining popularity among contributors of the communities for their ability to provide focused governance and decision-making. However, not everyone is convinced of their benefits, and a lively debate has emerged over its pros and cons.Why are they causing such a stir?On one side, members argue that subDAOs allow for increased specialization and delegation of tasks within the...

DAOs within DAOs? Too Complicated!
As DAO continues to evolve, a new type of subculture will emerge: the SubDAO. These smaller, specialized DAOs have been gaining popularity among contributors of the communities for their ability to provide focused governance and decision-making. However, not everyone is convinced of their benefits, and a lively debate has emerged over its pros and cons.Why are they causing such a stir?On one side, members argue that subDAOs allow for increased specialization and delegation of tasks within the...