Here is a summary of today's reframe: - Dialysis Protocol A gentler, “as‑needed” dialysis schedule helped ICU patients with kidney failure come off dialysis sooner, requiring fewer treatments and resulting in faster recovery. - Hepatitis B Cure Sign Adding an investigational small‑interfering RNA (elebsiran) to interferon led to higher rates of functional cure for chronic hepatitis B in a phase 2 study. - Improved mRNA Delivery Scientists developed new, degradable ionizable lipids that deliver mRNA more effectively, which could mean lower doses and better tolerability for vaccines. - Long-Lasting mRNA A chemical boostkept base‑modified mRNA stable for longer in lab models, potentially extending how long mRNA therapies work, meaning patients need fewer doses.