Here is a summary of today's reframe: - Breast Cancer: Many women with certain early breast cancers could safely skip chest-wall radiation after mastectomy without hurting 10-year survival. - Kidney Disease: The common antibody medicine Rituximab helped adults with hard-to-control relapsing nephrotic syndrome avoid relapses. - Psoriasis: An oral targeted peptide, Icotrokinra, improved psoriasis in adults and teens by blocking the IL-23 pathway.