AF(ATRIAL FIBRILATION) a risk factor for dementia in adults younger than 70 years.

This study (https://bit.ly/3bKwJs6) provides evidence that adults with AF experience an increase in the risk of developing dementia before the age of 65 to 70 years.

Of the six studies comprising approximately 1.6 million patients (mean age, 42-85 years), three reported the incidence of overall dementia at all ages and early-onset dementia. Diagnosis of AF was mainly identified by hospital discharge, admission records or after confirmed diagnosis, the researchers wrote.

AF was associated with increased risk for early-onset dementia (RR = 1.5; 95% CI, 1-2.26).

When the researchers used stroke-censored data and excluded vascular dementia, AF-related risk for early-onset dementia remained (RR = 1.38; 95% CI, 0.91-2.11).

The relationship between AF and early-onset dementia strengthened at older ages (RR for younger than 65 years =1.06; 95% CI, 0.54-2.06; RR for younger than 67 years = 1.81; 95% CI, 1.11-2.95; RR for younger than 70 years = 2.13; 95% CI, 1.58-2.87).

These findings are consistent with the overall association between AF and dementia risk. A causal link between AF and dementia in all age groups is also supported by findings of studies that have investigated the effect of AF therapy in dementia prevention.

AF(ATRIAL FIBRILATION) a risk factor for dementia in adults younger than 70 years.

This study (https://bit.ly/3bKwJs6) provides evidence that adults with AF experience an increase in the risk of developing dementia before the age of 65 to 70 years.

Of the six studies comprising approximately 1.6 million patients (mean age, 42-85 years), three reported the incidence of overall dementia at all ages and early-onset dementia. Diagnosis of AF was mainly identified by hospital discharge, admission records or after confirmed diagnosis, the researchers wrote.

AF was associated with increased risk for early-onset dementia (RR = 1.5; 95% CI, 1-2.26).

When the researchers used stroke-censored data and excluded vascular dementia, AF-related risk for early-onset dementia remained (RR = 1.38; 95% CI, 0.91-2.11).

The relationship between AF and early-onset dementia strengthened at older ages (RR for younger than 65 years =1.06; 95% CI, 0.54-2.06; RR for younger than 67 years = 1.81; 95% CI, 1.11-2.95; RR for younger than 70 years = 2.13; 95% CI, 1.58-2.87).

These findings are consistent with the overall association between AF and dementia risk. A causal link between AF and dementia in all age groups is also supported by findings of studies that have investigated the effect of AF therapy in dementia prevention.