After a long day in the lab frustrated, after following a highly cited methodology for the 6th time and not being able to characterise my cells. I spoke to all the smartest colleagues I knew and to my dismay everyone agreed that using published research methods in the lab never/rarely works. I was shell shocked; all the money, all the time, all the psychiatric break downs academics go through when they can not replicate a study and assuming it’s because they are useless. I headed to the inter...