Canurta.ethThe Satoshi Trials™: A Bitcoin Treasury Reserve Thesis
Date of Original Draft: Dec 15, 2024. Special Note: The initial Bitcoin price considered for these calculations is $100,000 USD per BTC given we [had on Dec 15th, 2024] passed the psychological price benchmark. Setting the Stage for Disruption Biotechnology has long grappled with the high costs and uncertainty of drug development, leaving promising therapies for diseases like ALS underfunded. At Canurta, we recognize the need for a transformative approach—one that not only addresses these cha...
Canurta.ethThe Canurta White Paper: Grounds for Further Investigation into Hemp Polyphenols
Written by Akeem Gardner, LLB Originally published on September 28, 2021 in Canurta’s Journal A quick note from Akeem before we begin: “2021 was an amazing year. From the launch of our company we grew by acquiring additional IP and investors who are supporting our mission to heal the world with novel polyphenols that have never been clinically explored before. Our team has shown so much growth in our journey of discovery and learning, and it’s now time to implement our DeSci strategy for our ...
Canurta.ethBuilt to Last, Not to Flex
A Founder's Note — Akeem Gardner"Thus, the deluded Bankrupt raves; Puts all upon a desprate Bet; Then plunges in the Southern Waves; Dipt over Head and Ears—in Debt."Life has a unique way of guiding us exactly where we need to be, often without us fully realizing it at the time. My journey led me to study law at the University of Kent, Canterbury, a path seemingly unrelated to my core passion—innovation and entrepreneurship. Yet, it was precisely in my Company Law class in October 2015 w...
an emerging biotech company using rare hemp polyphenols and DeSci to create safe and effective natural therapeutics
Canurta.ethThe Satoshi Trials™: A Bitcoin Treasury Reserve Thesis
Date of Original Draft: Dec 15, 2024. Special Note: The initial Bitcoin price considered for these calculations is $100,000 USD per BTC given we [had on Dec 15th, 2024] passed the psychological price benchmark. Setting the Stage for Disruption Biotechnology has long grappled with the high costs and uncertainty of drug development, leaving promising therapies for diseases like ALS underfunded. At Canurta, we recognize the need for a transformative approach—one that not only addresses these cha...
Canurta.ethThe Canurta White Paper: Grounds for Further Investigation into Hemp Polyphenols
Written by Akeem Gardner, LLB Originally published on September 28, 2021 in Canurta’s Journal A quick note from Akeem before we begin: “2021 was an amazing year. From the launch of our company we grew by acquiring additional IP and investors who are supporting our mission to heal the world with novel polyphenols that have never been clinically explored before. Our team has shown so much growth in our journey of discovery and learning, and it’s now time to implement our DeSci strategy for our ...
Canurta.ethBuilt to Last, Not to Flex
A Founder's Note — Akeem Gardner"Thus, the deluded Bankrupt raves; Puts all upon a desprate Bet; Then plunges in the Southern Waves; Dipt over Head and Ears—in Debt."Life has a unique way of guiding us exactly where we need to be, often without us fully realizing it at the time. My journey led me to study law at the University of Kent, Canterbury, a path seemingly unrelated to my core passion—innovation and entrepreneurship. Yet, it was precisely in my Company Law class in October 2015 w...
an emerging biotech company using rare hemp polyphenols and DeSci to create safe and effective natural therapeutics
Earlier this year, we at Canurta Inc. made the decision to enter Web3 publicly. The movement towards the real world value of blockchain technology and NFTs took the market by storm. By adopting a Web3 and blockchain focused strategy, we reaffirmed our confidence in overcoming the perceived “lack-of-focus” associated with biotech start-ups through decentralized and transparent advancements. Ever since that decision, we’ve been extremely impressed by everything we’ve learned, seen, and felt in connecting with multiple communities that have visions and goals of creating and delivering IRL impact to their internal collectors but to the world as well.
Attracted by the community, the apes, the roadmap but also their mission to support Alzheimer’s research, I, as an enterprising CEO, eagerly joined the Elderly Apes Retirement Club (EARC) where, as a budding biotech with novel molecules that hold neuroprotective qualities, knew we could add value.
On April 14th, 2022 the EARC will run a donation matching campaign with the American Alzheimer’s Society with the goal of giving away $100,000.00 to help #EndAlz. Today, we also want to share, that on behalf of the community, and Elderly Ape #888, our company will be pledging to investigate our novel hemp flavonoids and their potential as a neuroprotective agent to aid in the global fight to #EndAlz, whether as a natural supplement or drug.
A brief summary of why we’re excited about our flavonoids and Alzheimer’s:
We know that cannabis comprises an exclusive subset of prenylated flavonoids, the cannflavins (1). Based on peer-reviewed articles, we also know that cannflavins exhibit potent anti-inflammatory activity (2), and has a novel neuroprotective and anti-aggregatory effect relevant to Alzheimer’s disease (1). Furthermore, Shishtar et al. 2020 findings specified that a high flavonoid intake was associated with a lower risk of Alzheimer's and related dementias (3).
For the first time, there is a promising pathway towards making these novel compounds readily available on the market in their purity for humans, and our company, in association with our growing network of research partners at Canadian Universities and Research Colleges will be funding and supporting Alzheimer's preclinical trials, and publishing our findings on-chain and in academic journals, with acknowledgements to the community on behalf of EARC #888.
Our goal, by the time it's said and done, is to make this one of the most impactful peer-reviewed research articles to be submitted by an NFT #LFG 🚀
Looking forward to the world we have to do.
Together we will #HealTheWorld.
Akeem Gardner, EARC #888
For more information on our roadmap and scientific journey please reach out
If you’re interested in learning more about our molecules and our IP read our white paper below.
https://mirror.xyz/canurta.eth/SdS0mrpc_ZdY1BYElF_T-Cllj9LBa2btF_3QQy46bTA
Alzheimers References here:
(1) Eggers, C., Fujitani, M., Kato, R., & Smid, S. (2019). Novel cannabis flavonoid, cannflavin A displays both a hormetic and neuroprotective profile against amyloid β-mediated neurotoxicity in PC12 cells: Comparison with geranylated flavonoids, mimulone and diplacone. Biochemical pharmacology, 169, 113609. https://doi.org/10.1016/j.bcp.2019.08.011
(2) Rea, K. A., Casaretto, J. A., Al-Abdul-Wahid, M. S., Sukumaran, A., Geddes-McAlister, J., Rothstein, S. J., & Akhtar, T. A. (2019). Biosynthesis of cannflavins A and B from Cannabis sativa L. Phytochemistry, 164, 162–171. https://doi.org/10.1016/j.phytochem.2019.05.009
(3) Esra Shishtar, Gail T Rogers, Jeffrey B Blumberg, Rhoda Au, Paul F Jacques, Long-term dietary flavonoid intake and risk of Alzheimer disease and related dementias in the Framingham Offspring Cohort, The American Journal of Clinical Nutrition, Volume 112, Issue 2, August 2020, Pages 343–353, https://doi.org/10.1093/ajcn/nqaa079
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Earlier this year, we at Canurta Inc. made the decision to enter Web3 publicly. The movement towards the real world value of blockchain technology and NFTs took the market by storm. By adopting a Web3 and blockchain focused strategy, we reaffirmed our confidence in overcoming the perceived “lack-of-focus” associated with biotech start-ups through decentralized and transparent advancements. Ever since that decision, we’ve been extremely impressed by everything we’ve learned, seen, and felt in connecting with multiple communities that have visions and goals of creating and delivering IRL impact to their internal collectors but to the world as well.
Attracted by the community, the apes, the roadmap but also their mission to support Alzheimer’s research, I, as an enterprising CEO, eagerly joined the Elderly Apes Retirement Club (EARC) where, as a budding biotech with novel molecules that hold neuroprotective qualities, knew we could add value.
On April 14th, 2022 the EARC will run a donation matching campaign with the American Alzheimer’s Society with the goal of giving away $100,000.00 to help #EndAlz. Today, we also want to share, that on behalf of the community, and Elderly Ape #888, our company will be pledging to investigate our novel hemp flavonoids and their potential as a neuroprotective agent to aid in the global fight to #EndAlz, whether as a natural supplement or drug.
A brief summary of why we’re excited about our flavonoids and Alzheimer’s:
We know that cannabis comprises an exclusive subset of prenylated flavonoids, the cannflavins (1). Based on peer-reviewed articles, we also know that cannflavins exhibit potent anti-inflammatory activity (2), and has a novel neuroprotective and anti-aggregatory effect relevant to Alzheimer’s disease (1). Furthermore, Shishtar et al. 2020 findings specified that a high flavonoid intake was associated with a lower risk of Alzheimer's and related dementias (3).
For the first time, there is a promising pathway towards making these novel compounds readily available on the market in their purity for humans, and our company, in association with our growing network of research partners at Canadian Universities and Research Colleges will be funding and supporting Alzheimer's preclinical trials, and publishing our findings on-chain and in academic journals, with acknowledgements to the community on behalf of EARC #888.
Our goal, by the time it's said and done, is to make this one of the most impactful peer-reviewed research articles to be submitted by an NFT #LFG 🚀
Looking forward to the world we have to do.
Together we will #HealTheWorld.
Akeem Gardner, EARC #888
For more information on our roadmap and scientific journey please reach out
If you’re interested in learning more about our molecules and our IP read our white paper below.
https://mirror.xyz/canurta.eth/SdS0mrpc_ZdY1BYElF_T-Cllj9LBa2btF_3QQy46bTA
Alzheimers References here:
(1) Eggers, C., Fujitani, M., Kato, R., & Smid, S. (2019). Novel cannabis flavonoid, cannflavin A displays both a hormetic and neuroprotective profile against amyloid β-mediated neurotoxicity in PC12 cells: Comparison with geranylated flavonoids, mimulone and diplacone. Biochemical pharmacology, 169, 113609. https://doi.org/10.1016/j.bcp.2019.08.011
(2) Rea, K. A., Casaretto, J. A., Al-Abdul-Wahid, M. S., Sukumaran, A., Geddes-McAlister, J., Rothstein, S. J., & Akhtar, T. A. (2019). Biosynthesis of cannflavins A and B from Cannabis sativa L. Phytochemistry, 164, 162–171. https://doi.org/10.1016/j.phytochem.2019.05.009
(3) Esra Shishtar, Gail T Rogers, Jeffrey B Blumberg, Rhoda Au, Paul F Jacques, Long-term dietary flavonoid intake and risk of Alzheimer disease and related dementias in the Framingham Offspring Cohort, The American Journal of Clinical Nutrition, Volume 112, Issue 2, August 2020, Pages 343–353, https://doi.org/10.1093/ajcn/nqaa079
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