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Crypto Digest 53 (November 2025)

Trends and innovations

News

ETH exceeding BTC in treasury companies (by share of supply)

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ETH exceeding BTC in treasury companies

Coinmarketcap index (CMC20)

CoinMarketCap announced $CMC20, a DeFi-native tradable crypto index token Built in partnership with @reserveprotocol & deployed by @lista_dao, now available on @PancakeSwap & @TrustWallet. Powered by @CelerNetwork, new assets are bridged onto BNB Chain, allowing timely & easy access.

CMC20 tracks the Top 20 largest cryptocurrencies by market cap (ex-stablecoins & ineligible assets), giving you broad exposure to L1s, infrastructure, DeFi, exchange tokens & more, all in just one click.

Users get:

  • Delta-neutral use cases

  • Collateralized lending

  • Automated portfolio rotation

  • Onchain auditability 

  • One-tap diversification

  • Zero need to self-construct portfolios.

Ongoing integrations with CEXs, DEXs, Wallets, Platforms & fintech partners. • Upcoming lending & yield-generation utilities for CMC20 holders Explore the product on Reserve

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CoinMarketCap 20 Index DTF
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Sourse: Dune
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x402 analytics

Global statistics for the x402 ecosystem past 30 days

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Top addresses that have received x402 transfers and are listed in the Bazaar. This month leader is AgentPayWall-402: AIsa platform connects AI Agents with digital resource providers through programmable, per-call micropayments — effectively turning API, model, or GPU cycle into a machine-tradable asset.

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The most popular agents on x402scan is [t54] x402-secure Agent, the first risk & security intelligence to build the trust layer of x402.

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Santiment

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Top chains by Fee

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Returns across traditional and digital assets

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Volatility increased in October, while open interest dropped.

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ETF Net Flow last month: -$552.10M

The net capital inflows and outflows for cryptocurrency Exchange-Traded Funds (ETFs) 

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Total Cryptos Created last 30d are 1,308,635

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Indices

CMC100 falls for second month in a row

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According Defillama, an indexes protocols' TVL is $786.58M

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Top 5 indexes protocols by revenue in November 2025.

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CeFi index is the leader by ROI last month on SoSoValue.

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Thanks to the growth of Telcoin ($TEL), the PayFi index is falling less than the others.

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PayFi index constituent currencies

Coins that are used most frequently in recently created indices on Indexy

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Mindshare

Sectors & subsectors by Mindshare in November 2025, according Messari.

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Major Reasons for the Mindshare Spike in the AI:

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Major Reasons for the Mindshare Spike in the Perpetuals Sub-Sector:

  • DEX perpetual trading volume reached a record $1.2T in October 2025. November 2025 marked the 14th consecutive month of growth in DEX perpetual volumes.

  • Expansion into Real-World Asset (RWA) and Equity Perpetuals with Injective, ApeX Protocol, Hyperliquid.

Crypto venture rounds

According funding.decentralised.co 

  • Total funding: $252.3M (-41% vs prev. 30d)

  • Number of Deals (30d): 42 (+56% vs prev. 30d)

  • Average Deal Size (30d): $6.5M (-65% vs prev. 30d)

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