On February 9, 2025, "The Realized Summit," hosted by 499 and co-hosted by Pharos Network and RedStone, was successfully held at Soho House, Hong Kong. As one of the flagship side events during Consensus Hong Kong, the summit gathered industry leaders from top global institutions including Bitget, Sei Labs, Animoca Brands, HashKey, and Spartan, attracting over 2,300 registered attendees. Centering on the theme "Realized," the summit delved deep into Real-World Assets (RWA), PayFi, and open in...

Date: December 5, 2025 Event: 499 x HETU | AITOPIA [NO.002] Topic: AI Agents x Biomedicine: Powering The Next Breakthrough in HealthcareOver the past decade, AI has transformed many aspects of biomedical research—from predictive modeling to diagnostics. However, we are now standing at a new critical juncture: a leap from passive "AI Tools" to autonomous "AI Agents". When AI Agents begin to intervene in drug discovery, clinical decision-making, and longevity science, this represents more than ...

On October 3rd, The Scaling Summit, hosted by 499, was successfully held during TOKEN2049 Singapore. Centered around the three core themes of "Ethereum · AI · Blockchain for Good," three parallel sessions and 61 distinguished guests explored the next generation of the intelligent economy.

自2018年成立以来，499已成为行业内最具影响力的OG 社区之一。我们聚焦 AI、DeSci、 Longevity、RWA与女性科技，作为拥有超过30位核心成员、遍布全球10+国家的去中心化 组织 (DAO)，我们致力于构建全球共生网络，连接创造者与行动者，推动新兴技术与人类未来的协同进化。 499旗下的女性社区，开创了行业女性去中心化组织的先河，汇聚了全球最具创新精神的女性建设者。

On February 9, 2025, "The Realized Summit," hosted by 499 and co-hosted by Pharos Network and RedStone, was successfully held at Soho House, Hong Kong. As one of the flagship side events during Consensus Hong Kong, the summit gathered industry leaders from top global institutions including Bitget, Sei Labs, Animoca Brands, HashKey, and Spartan, attracting over 2,300 registered attendees. Centering on the theme "Realized," the summit delved deep into Real-World Assets (RWA), PayFi, and open in...

Date: December 5, 2025 Event: 499 x HETU | AITOPIA [NO.002] Topic: AI Agents x Biomedicine: Powering The Next Breakthrough in HealthcareOver the past decade, AI has transformed many aspects of biomedical research—from predictive modeling to diagnostics. However, we are now standing at a new critical juncture: a leap from passive "AI Tools" to autonomous "AI Agents". When AI Agents begin to intervene in drug discovery, clinical decision-making, and longevity science, this represents more than ...

On October 3rd, The Scaling Summit, hosted by 499, was successfully held during TOKEN2049 Singapore. Centered around the three core themes of "Ethereum · AI · Blockchain for Good," three parallel sessions and 61 distinguished guests explored the next generation of the intelligent economy.